GATA2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 11103-1-AP

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Freight/Packing

Con: 54 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HEK-293 cells, K-562 cells, mouse heart tissue, mouse liver tissue, Raji cells, rat heart tissue, rat liver tissue

Positive IHC detected in:
human lymphoma tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
GATA binding protein 2

Calculated molecular weight:

Observed molecular weight:
60-66kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GATA2

Synonyms
FLJ45948, GATA binding protein 2, GATA2, NFE1B
Background

GATA2 is a member of GATA family of transcription factors that contains zinc fingers in DNA binding domain. GATA2 acts as a transcriptinal activator that regulates endothelin-1 expression in endothelial cells. Together with GATA3, GATA2 regulates adipocyte differentiation through molecular control of the preadpocyte-adipocyte transition. It also affect the activity of Rho inhibitor p190RhoGAP that controls capillary network formation in vitro and retinal angiogenesis in vivo.


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