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- KD/KO Validated
GSTM3 Polyclonal antibody
GSTM3 Polyclonal Antibody for IHC, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat and More (2)
WB, IP, IHC, ELISA
Cat no : 15214-1-AP
|Positive WB detected in||mouse testis tissue, human testis tissue, rat testis tissue|
|Positive IP detected in||mouse testis tissue|
|Positive IHC detected in||human testis tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 4 publications below|
|WB||See 12 publications below|
|IHC||See 5 publications below|
15214-1-AP targets GSTM3 in WB, IP, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat, bovine, sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||GSTM3 fusion protein Ag7375|
|Full Name||glutathione S-transferase mu 3 (brain)|
|Calculated molecular weight||27 kDa|
|Observed molecular weight||27-29 kDa|
|GenBank accession number||BC000088|
|Gene ID (NCBI)||2947|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
GSTM3 is a cytosolic enzyme involved in prostaglandin and leukotriene synthesis and in the metabolization of toxic compounds, such as chemotherapeutic drugs, insecticides, herbicides, carcinogens, and by-products of oxidative stress. GSTM3 is expressed in testis, brain, lung, and lymphocytes. GSTM3 have been reported to be dysregulated in cancers like prostate cancer and colon cancer.
|Product Specific Protocols|
|WB protocol for GSTM3 antibody 15214-1-AP||Download protocol|
|IHC protocol for GSTM3 antibody 15214-1-AP||Download protocol|
|IP protocol for GSTM3 antibody 15214-1-AP||Download protocol|
|Click here to view our Standard Protocols|
TMEM41B acts as an ER scramblase required for lipoprotein biogenesis and lipid homeostasis.
GSTM3 deficiency impedes DNA mismatch repair to promote gastric tumorigenesis via CAND1/NRF2-KEAP1 signaling.
Part Fibre Toxicol
Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies.
The fetal ovary exhibits temporal sensitivity to a 'real-life' mixture of environmental chemicals.
Br J Cancer
Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression.
Glutathione S-Transferase Mu-3 Predicts a Better Prognosis and Inhibits Malignant Behavior and Glycolysis in Pancreatic Cancer.