HADHA Antibody 9 Publications

Rabbit Polyclonal| Catalog number: 10758-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, MCF-7 cells, MDA-MB-453s cells, Jurkat cells, mouse liver tissue, HeLa cells, rat kidney tissue, HepG2 cells, mouse kidney tissue, mouse heart tissue, HeLa cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human colon cancer tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue, human testis tissue

Positive IF detected in:
HeLa cells, HepG2 cells

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:5000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit

Calculated molecular weight:
83 kDa

Observed molecular weight:
70-79 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
HADHA

Synonyms
78 kDa gastrin binding protein, ECHA, HADH, HADHA, LCHAD, MTPA, TP ALPHA
Background

HADHA(Trifunctional enzyme subunit alpha, mitochondrial) is also named as HADH,78 kDa gastrin-binding protein.It belongs to the enoyl-CoA hydratase/isomerase family in the N-terminal section and the 3-hydroxyacyl-CoA dehydrogenase family in the central section.It harbors the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.Defects in HADHA are a cause of trifunctional protein deficiency (TFP deficiency) and long-chain 3-hydroxyl-CoA dehydrogenase deficiency (LCHAD deficiency) and maternal acute fatty liver of pregnancy (AFLP).


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