HDAC10 Polyclonal antibody

HDAC10 Polyclonal Antibody for WB, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 24913-1-AP


HD10, HDAC10, histone deacetylase 10

Tested Applications

Positive WB detected infetal human brain tissue, mouse thymus tissue
Positive IHC detected inhuman colon cancer tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inMCF-7 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

24913-1-AP targets HDAC10 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen HDAC10 fusion protein Ag18470
Full Name histone deacetylase 10
Calculated Molecular Weight 669 aa, 71 kDa
Observed Molecular Weight 68 kDa
GenBank Accession NumberBC125083
Gene Symbol HDAC10
Gene ID (NCBI) 83933
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

HDAC10, also named as Histone deacetylase 10, is a 669 amino acid protein, which is widely expressed with high levels in liver and kidney. HDAC10, which belongs to the class IIb subfamily, has an active deacetylase domain (DAC) and a catalytically inactive leucine-rich domain (LRD). HDAC10 is determined that it plays a role in homologous recombination, promotes autophagy and survival in neuroblastoma cells, suppresses cervical cancer metastasis and facilitates the cell cycle.


Product Specific Protocols
WB protocol for HDAC10 antibody 24913-1-APDownload protocol
IHC protocol for HDAC10 antibody 24913-1-APDownload protocol
IF protocol for HDAC10 antibody 24913-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols


mouse, ratWB

Kidney Int

Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy.

Authors - Xiaojie Wang

Oncol Lett

HDAC10 expression is associated with DNA mismatch repair gene and is a predictor of good prognosis in colon carcinoma.

Authors - Xiangxiang Tao

Cell Death Dis

WNT5A promotes the metastasis of esophageal squamous cell carcinoma by activating the HDAC7/SNAIL signaling pathway.

Authors - Yingtong Feng

J Cell Mol Med

RNA m5C methylation orchestrates BLCA progression via macrophage reprogramming

Authors - Dali Yan

Discov Oncol

Elevated histone deacetylase 10 expression promotes the progression of clear cell renal cell carcinoma by Notch-1-PTEN signaling axis

Authors - Bin Zheng