HuR Antibody 13 Publications

Rabbit Polyclonal| Catalog number: 11910-1-AP

Featured Product KD/KO validated

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Con: 64 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
HEK-293 cells, RAW264.7 , hESC cells, HL-60 cells, Jurkat cells, A431 cells, HeLa cells, NIH/3T3 cells, K-562 cells

Positive IP detected in:
HEK-293 cells

Positive IHC detected in:
human ovary tumor tissue, human breast cancer tissue, human pancreas tissue, human skin tissue

Positive IF detected in:
MCF-7 cells, Ethacrynic acid treated HepG2 cells

Positive FC detected in:
MCF-7 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)

Calculated molecular weight:
326aa,36 kDa

Observed molecular weight:
30-37 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

ELAV like protein 1, ELAV1, ELAVL1, Hu antigen R, Hua, HuR, MelG

ELAVL1, also named as HUR, belongs to the RRM elav family. It is involved in 3'-UTR ARE-mediated MYC stabilization. ELAVL1 binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, ELAVL1 binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.

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