IL-17A Polyclonal antibody

IL-17A Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG




WB, IF, FC, IHC, ELISA, Cell treatment



Cat no : 13082-1-AP


CTLA 8, CTLA8, IL 17, IL 17A, IL17, IL-17, IL17A, interleukin 17A

Tested Applications

Positive IHC detected inhuman colon cancer tissue, human cervical cancer tissue, human stomach cancer tissue, human colon tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

13082-1-AP targets IL-17A in WB, IF, FC, IHC, ELISA, Cell treatment applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IL-17A fusion protein Ag3733
Full Name interleukin 17A
Calculated Molecular Weight 155 aa, 18 kDa
GenBank Accession NumberBC067505
Gene Symbol IL17A
Gene ID (NCBI) 3605
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased. This antibody got 32-35 kDa band in western blot, maybe due to homodimer formation and differential glycosylations.


Product Specific Protocols
IHC protocol for IL-17A antibody 13082-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Autoimmun

IL-17 is expressed on beta and alpha cells of donors with type 1 and type 2 diabetes.

Authors - Sakthi Rajendran

J Med Chem

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J Invest Dermatol

Reduced Il17a expression distinguishes a Ly6c(lo)MHCII(hi) macrophage population promoting wound healing.

Authors - Rodero Mathieu P MP

Arch Oral Biol

Age-related changes of CD4+ T cell migration and cytokine expression in germ-free and SPF mice periodontium.

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Cell Physiol Biochem

Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis.

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J Cell Mol Med

Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.

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