ST2 Polyclonal antibody
ST2 Polyclonal Antibody for IHC, WB,ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IF,ELISA
Conjugate
Unconjugated
Cat no : 11920-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | mouse brain tissue, multi-cells |
| Positive IHC detected in | human lung cancer tissue, human heart tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| KD/KO | See 1 publications below |
| WB | See 9 publications below |
| IHC | See 8 publications below |
| IF | See 6 publications below |
Product Information
11920-1-AP targets ST2 in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ST2 fusion protein Ag2555 |
| Full Name | interleukin 1 receptor-like 1 |
| Calculated molecular weight | 63 kDa, 37 kDa, 30 kDa |
| Observed molecular weight | 30 kDa, 40 kDa |
| GenBank accession number | BC030975 |
| Gene symbol | IL1RL1 |
| Gene ID (NCBI) | 9173 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Protein ST2, also known as IL1RL1, is a member of the interleukin 1 receptor family. The gene of ST2 encodes three splice variants: a soluble secreted form, a transmembrane form and a form of undetermined localization.This antibody recognizes at least 80kd, 40kd and 30kd forms in different tissues and cells.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for ST2 antibody 11920-1-AP | Download protocol |
| IHC protocol for ST2 antibody 11920-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Int Immunopharmacol Interleukin-33 prevents the development of autoimmune diabetes in NOD mice. | ||
J Mol Cell Cardiol Yin-Yang 1 transcription factor modulates ST2 expression during adverse cardiac remodeling post-myocardial infarction. | ||
Cells Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation. | ||
Med Sci Monit Downregulated miR-524-5p Participates in the Tumor Microenvironment of Ameloblastoma by Targeting the Interleukin-33 (IL-33)/Suppression of Tumorigenicity 2 (ST2) Axis. | ||
Clin Exp Dermatol Interleukin-33 affects cytokine production by keratinocytes in vitiligo. |
