Product Information
19689-1-AP targets INCENP in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide Predict reactive species |
| Full Name | inner centromere protein antigens 135/155kDa |
| Calculated Molecular Weight | 105 kDa |
| GenBank Accession Number | NM_001040694 |
| Gene Symbol | INCENP |
| Gene ID (NCBI) | 3619 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9NQS7 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
INCENP belongs to the INCENP family. It’s component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. INCENP probably acts through association with AURKB or AURKC. It seems to bind directly to microtubules. The antibody is to INCENP with Y(822-phopho) and S(831-phopho).
