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ING1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17921-1-AP

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Con: 26 μg/150 μl

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Tested Applications

Applications:
WB, ELISA
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ING1 Antibody WB mouse liver tissue 17921-1-AP

mouse liver tissue were subjected to SDS PAGE followed by western blot with 17921-1-AP( ING1 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

Species specificity:
human, mouse, rat
Positive WB detected in:
mouse liver tissue, A375 cells
Recommended dilution:
WB : 1:500-1:1000
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
ING1 fusion protein Ag12338
Full name:
inhibitor of growth family, member 1
Calculated molecular weight:
279aa,32 kDa;422aa,47 kDa
Observed molecular weight:
47 kDa
GenBank accession number:
BC093942
Gene ID (NCBI):
3621
Gene symbol
ING1
Synonyms
ING1, Inhibitor of growth protein 1, p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

Background

ING1, also inhibitor of growth protein 1, is a 422 amino acid protein, which contains 1 PHD-type zinc finger and belongs to the ING family. ING1 localizes in the nucleus and interacts with TP53. It exsits as varous isoforms and isoform 1 is a 47 kDa protein. Isoform 2 is a 33 kDa protein and expressed in all normal tissues, as well as in all breast cancer and melanoma cell lines examined. ING1 cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. It is implicated as a tumor suppressor gene.


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