ING1 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17921-1-AP

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Freight/Packing

Con: 26 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue, A375 cells, mouse liver tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
inhibitor of growth family, member 1

Calculated molecular weight:
279aa,32 kDa;422aa,47 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ING1

Synonyms
ING1, Inhibitor of growth protein 1, p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Background

ING1, also inhibitor of growth protein 1, is a 422 amino acid protein, which contains 1 PHD-type zinc finger and belongs to the ING family. ING1 localizes in the nucleus and interacts with TP53. It exsits as varous isoforms and isoform 1 is a 47 kDa protein. Isoform 2 is a 33 kDa protein and expressed in all normal tissues, as well as in all breast cancer and melanoma cell lines examined. ING1 cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. It is implicated as a tumor suppressor gene.


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