ITPR3 Recombinant antibody

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  WB analysis using 84693-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84693-1-RR (ITPR3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

ITPR3 Recombinant Antibody for WB, ELISA

Cat No. 84693-1-RR

Clone No.241859B6

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

IP3R3, IP3R 3, IP3R, InsP3R3, 241859B6

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Tested Applications

• Positive WB detected in: HeLa cells, L02 cells, HepG2 cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

84693-1-RR targets ITPR3 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Peptide
• Full Name: inositol 1,4,5-triphosphate receptor, type 3
• Calculated Molecular Weight: 304 kDa
• Observed Molecular Weight: 250-300 kDa
• GenBank Accession Number: NM_002224
• Gene Symbol: ITPR3
• Gene ID (NCBI): 3710
• RRID: AB_3672109
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: Q14573
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ITPRs family have three members: ITPR1, ITPR2 and ITPR3. For ITPR3, it is associated with cervical squamous cell carcinoma, glioblastoma, cholangiocarcinoma and other cancers. Inositol 1,4, 5-triphosphate receptor type 3 (ITPR3) was found to be apical-located in bile duct cells, and disruption of lipid raft in the segregated bile duct unit (IBDU) redistributes ITPR3 and impairs Ca2+ waves. (PMID: 35580861, PMID:35852334)