Published Applications
| WB | See 1 publications below |
| IHC | See 1 publications below |
Product Information
17791-1-AP targets Jagged1 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Jagged1 fusion protein Ag11891 Predict reactive species |
| Full Name | jagged 1 (Alagille syndrome) |
| Calculated Molecular Weight | 1218 aa, 134 kDa |
| GenBank Accession Number | BC098393 |
| Gene Symbol | Jagged1 |
| Gene ID (NCBI) | 182 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P78504 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
JAG1, also named as JAGL1, CD339 and Jagged1, is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It may be involved in cell-fate decisions during hematopoiesis. JAG1 seems to be involved in early and late stages of mammalian cardiovascular development. It inhibits myoblast differentiation. JAG1 enhances fibroblast growth factor-induced angiogenesis. JAG1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Publications
| Species | Application | Title |
|---|---|---|
Front Immunol Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma |
