Cytokeratin 13 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 10164-2-AP

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Freight/Packing

Con: 46 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A431 cells, A431 cells, HEK-293 cells, mouse skin tissue

Positive IP detected in:
A431 cells

Positive IHC detected in:
human cervical cancer tissue, human breast cancer tissue, human cervical cancer tissue, human lung cancer tissue, human nephroblastoma tissue, human oesophagus tissue

Positive IF detected in:
A431 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:50-1:500
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
keratin 13

Calculated molecular weight:
50 kDa

Observed molecular weight:
50 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
KRT13

Synonyms
CK 13, CK13, Cytokeratin 13, K13, keratin 13, KRT13
Background

Keratin 13 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in keratin 13 gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2.


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