- Featured Product
- KD/KO Validated
Cytokeratin 7-specific Polyclonal antibody
Cytokeratin 7-specific Polyclonal Antibody for FC, IF, IHC, IP, WB, ELISA
Cat no : 17513-1-AP
Validation Data Gallery
|Positive WB detected in||A431 cells, HeLa cells, HepG2 cells|
|Positive IP detected in||HepG2 cells|
|Positive IHC detected in||human lung cancer tissue, human kidney tissue, human ovary tumor tissue, human breast cancer tissue, human cervical cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HepG2 cells|
|Positive FC detected in||HeLa cells|
|Western Blot (WB)||WB : 1:5000-1:50000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:1000-1:4000|
|Immunofluorescence (IF)||IF : 1:200-1:800|
|Sample-dependent, check data in validation data gallery|
17513-1-AP targets Cytokeratin 7-specific in WB, IP, IHC, IF, FC, ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Full Name||keratin 7|
|Calculated molecular weight||51 kDa|
|Observed molecular weight||51 kDa|
|GenBank accession number||NM_005556|
|Gene ID (NCBI)||3855|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. KRT7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. This antibody is specifically against KRT7.
|Product Specific Protocols|
|WB protocol for Cytokeratin 7-specific antibody 17513-1-AP||Download protocol|
|IHC protocol for Cytokeratin 7-specific antibody 17513-1-AP||Download protocol|
|IF protocol for Cytokeratin 7-specific antibody 17513-1-AP||Download protocol|
|IP protocol for Cytokeratin 7-specific antibody 17513-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Clin Cancer Res
Integrative Genomic Analysis of Gemcitabine Resistance in Pancreatic Cancer by Patient-derived Xenograft Models.
A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner.
Proc Natl Acad Sci U S A
Up-regulation of CD81 inhibits cytotrophoblast invasion and mediates maternal endothelial cell dysfunction in preeclampsia.
USP13 promotes development and metastasis of high-grade serous ovarian carcinoma in a novel mouse model.
Eur J Cancer
Correlation between drug sensitivity profiles of circulating tumour cell-derived organoids and clinical treatment response in patients with pancreatic ductal adenocarcinoma.
Mol Ther Nucleic Acids
miR21 modulates the Hippo signaling pathway via interference with PP2A Bβ to inhibit trophoblast invasion and cause preeclampsia