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- KD/KO Validated
Galectin-9 Polyclonal antibody
Galectin-9 Polyclonal Antibody for IF, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
WB, IP, IHC, IF, ELISA
Cat no : 17938-1-AP
Validation Data Gallery
|Positive WB detected in||U-937 cells, HeLa cells, HepG2 cells, NIH/3T3 cells, HL-60 cells, SGC-7901 cells|
|Positive IP detected in||SGC-7901 cells|
|Positive IF detected in||HeLa cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
17938-1-AP targets Galectin-9 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Galectin-9 fusion protein Ag12209|
|Full Name||lectin, galactoside-binding, soluble, 9|
|Calculated molecular weight||323 aa, 36 kDa|
|Observed molecular weight||45 kDa|
|GenBank accession number||BC110340|
|Gene ID (NCBI)||3965|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
The galectins, formerly known as S-type lectins, are a family of β-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-9 (LGALS9) is a tandem repeat-type member of the galectin family. It has three isoforms (named galectin-9L, galectin-9M, and galectin-9S): long type of 355 amino acids, medium type of 323 amino acids, and short type of 311 amino acids. Galectin-9 is ubiquitously expressed in a variety of tissues, including lymph nodes and spleen, and overexpressed in Hodgkin disease tissue. It is involved in chemoattraction, apoptosis, and the regulation of cell differentiation and has anti-allergic effects. It has been reported that galectin-9 is a ligand for Tim-3, through which galectin-9 can induce T-helper type 1 lymphocyte (Th1) death.
|Product Specific Protocols|
|WB protocol for Galectin-9 antibody 17938-1-AP||Download protocol|
|IF protocol for Galectin-9 antibody 17938-1-AP||Download protocol|
|IP protocol for Galectin-9 antibody 17938-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Front Mol Neurosci
Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson’s disease
J Nutr Biochem
Isothiocyanates attenuate immune checkpoint blockage therapy in gastric cancer via induction of PD-L1 expression
Galectin-9/TIM-3 as a Key Regulator of Immune Response in Gliomas With Chromosome 1p/19q Codeletion.
Prognostic Value and Biological Function of Galectins in Malignant Glioma.
Stem Cell Res Ther
Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9.
Int J Oncol
Role of downregulation of galectin-9 in the tumorigenesis of gastric cancer.