LIMS2 Polyclonal antibody, PBS Only

• 

  WB analysis using 55300-1-AP (same clone as 55300-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55300-1-AP (LIMS2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55300-1-PBS in a different storage buffer formulation.

LIMS2 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 55300-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

LIM like protein 2, PINCH2, PINCH-2

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Product Information

55300-1-PBS targets LIMS2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: LIM and senescent cell antigen-like domains 2
• Calculated Molecular Weight: 39 kDa
• Observed Molecular Weight: 35-40 kDa
• GenBank Accession Number: NM_017980
• Gene Symbol: LIMS2
• Gene ID (NCBI): 55679
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q7Z4I7
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

LIMS2, also known as PINCH2, is a member of a small family of focal adhesion proteins. LIMS2 contains five LIM domains, each domain forming two zinc fingers, which permit interactions that regulate cell shape and migration. Along with integrin-linked kinase and parvin, LIMS2 is a component of a complex that mediates multiple protein-protein interactions at adhesion sites between cells and the extracellular matrix (ECM) (PMID: 12167643). Mutations in LIMS2 are associated with a novel muscular dystrophy, severe cardiomyopathy and triangular tongues(PMID: 25589244).