LMOD1 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 15117-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human skeletal muscle tissue, HeLa cells, mouse bladder tissue, mouse skeletal muscle tissue, mouse uterus tissue

Positive IP detected in:
mouse skeletal muscle tissue

Positive IHC detected in:
human ovary tumor tissue

Positive IF detected in:
A375 cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
leiomodin 1 (smooth muscle)

Calculated molecular weight:
67 kDa

Observed molecular weight:
85 kDa or 64 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
LMOD1

Synonyms
1D, 64 kDa autoantigen 1D, 64 kDa autoantigen 1D3, 64 kDa autoantigen D1, 64kD, D1, FLJ55689, Leiomodin 1, leiomodin 1 (smooth muscle), Leiomodin, muscle form, LMOD1, SM LMOD, Smooth muscle leiomodin
Background

LMOD1 was initially identified as a 64-kDa autoantigen in an expression screen with sera from patients with Hashimoto’s thyroiditis. Recently immunohistochemistry and immunoblotting of LMOD1 demonstrated its highly restrictive pattern of expression in SMC lineages,like adult aorta, and bladder. LMOD1 is also shown to exhibit an embryonic and adult expression pattern. These data identify LMOD1 as a new SMC-restricted gene associated with the SMC differentiated phenotype.


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