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  • KD/KO Validated

Perilipin 5 Polyclonal antibody

Perilipin 5 Polyclonal Antibody for IHC, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, pig, mouse

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 26951-1-AP

Synonyms

LSDP5, OXPAT, Perilipin 5, PLIN5



Tested Applications

Positive WB detected inmouse heart tissue, mouse liver tissue, pig heart tissue
Positive IHC detected inhuman liver tissue, human heart tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 26951-1-AP is Perilipin 5 Fusion Protein expressed in E. coli.

Tested Reactivity human, pig, mouse
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Perilipin 5 fusion protein Ag25272
Full Name lipid storage droplet protein 5
Calculated molecular weight 463 aa, 51 kDa
Observed molecular weight 51-55 kDa
GenBank accession numberBC131524
Gene symbol LSDP5
Gene ID (NCBI) 440503
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Perilipin 5 (also known as LSDP5/OXPAT) is a lipid droplet (LD) coat protein that promotes association of LDs with mitochondria and is mainly present in tissues with a high fat-oxidative capacity, such as heart, skeletal muscles and brown adipose tissue. It plays an important role in the regulation of cardiac lipid storage and function.

Protocols

Product Specific Protocols
WB protocol for Perilipin 5 antibody 26951-1-APDownload protocol
IHC protocol for Perilipin 5 antibody 26951-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Biochem Biophys Res Commun

ER stress mediated degradation of diacylglycerol acyltransferase impairs mitochondrial functions in TMCO1 deficient cells.

Authors - Xi Wang
humanWB

Cells

Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells.

Authors - Yanjie Tan
  • KD Validated
mouseWB

Int J Mol Sci

Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression.

Authors - Miljenko V Panajatovic
mouseWB

Biochem Biophys Res Commun

Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.

Authors - Jie Feng
humanWB,IF

Hum Cell

Aryl hydrocarbon receptor promotes lipid droplet biogenesis and metabolic shift in respiratory Club cells.

Authors - Hsueh-Chun Wang
mouseWB

EMBO Rep

miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle.

Authors - Hui Wang