Cat no : lcg
DNA plasmid encoding for anti-Lamin VHH (anti-Lamin Nanobody) fused to TagGFP2.
|The Lamin-Chromobody visualizes the nuclear lamina.
• Easily transfect your cells with the Lamin-Chromobody plasmid
• Visualize the nuclear lamina without interfering with its cellular functions
• Monitor the nuclear integrity and morphology during live cell microscopy
|Trace the nuclear lamina in live cells in real-time
Monitor the nuclear integrity and morphology
Use the Lamin-Chromobody® as a biosensor for real-time assays of mitosis or apoptosis
|Lamin A/C, tested in human cell lines (HeLa, U2OS) and insect S2 cells.
|Mammalian expression vector
|Constitutive CMV IE
|With the Lamin-Chromobody plasmid you receive the sequence information of the Alpaca antibody to Lamin fused to TagGFP2, as well as the full vector sequence.
|Transfection of Chromobody plasmids into mammalian cells can be done with standard DNA-transfection methods, e.g. lipofection (Lipofectamine 2000® from Thermo Scientific), according to the manufacturer’s protocol for the transfection reagent. Please choose the transfection method that works the best for your cell type.
|Wide-field epifluorescence microscopy; confocal microscopy
|Shipped at ambient temperature. Store at -20 °C
Nat Cell Biol
A transient pool of nuclear F-actin at mitotic exit controls chromatin organization.
GPCR-induced calcium transients trigger nuclear actin assembly for chromatin dynamics.
Fluorescent protein tagging of adenoviral proteins pV and pIX reveals 'late virion accumulation compartment'.
J Cell Sci
The prophase oocyte nucleus is a homeostatic G-actin buffer.
A novel epitope tagging system to visualize and monitor antigens in live cells with chromobodies.
Cell Mol Bioeng
Characterization of 3D Printed Stretching Devices for Imaging Force Transmission in Live-Cells.