TAK1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 12330-2-AP

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Freight/Packing

Con: 43 μg/150 μl

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Species specificity:
human, hamster, mouse

Positive WB detected in:
CHO cells, MCF-7 cells, A2780 cells, A431 cells, A375 cells, mouse heart tissue, COLO 320 cells, HeLa cells, K-562 cells, SKOV-3 cells

Positive IHC detected in:
human prostate cancer tissue, human brain tissue, mouse brain tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:100-1:400

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
mitogen-activated protein kinase kinase kinase 7

Calculated molecular weight:
579aa,64 kDa

Observed molecular weight:
64 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
MAP3K7

Synonyms
MAP3K7, TAK1, TGF beta activated kinase 1, TGF1a
Background

MAP3K7(Mitogen-activated protein kinase kinase kinase 7) is also named as TAK1 and belongs to the MAP kinase kinase kinase subfamily.It plays an important role in the cascades of cellular responses evoked by changes in the environment.It has been linked to interleukin-1 receptor and tumor necrosis factor receptor signaling(PMID: 16186825).It has 4 isoforms (53055 kDa; 64-70 kDa and 75-80 kDa)produced by alternative splicing.


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