Matrilin 2 Polyclonal antibody

Matrilin 2 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IF, ELISA

Conjugate

Unconjugated

Cat no : 24064-1-AP

Synonyms

MATN2, Matrilin 2



Tested Applications

Positive WB detected inNIH/3T3 cells, HEK-293 cells, mouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 24064-1-AP is Matrilin 2 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivitymouse, zebrafish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Matrilin 2 fusion protein Ag21113
Full Name matrilin 2
Calculated molecular weight 107 kDa
Observed molecular weight 120-150 kDa
GenBank accession numberBC010444
Gene symbol MATN2
Gene ID (NCBI) 4147
Conjugate Unconjugated
Form Liquid
Purification Method Antigen Affinity purified
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The matrilins represent a new family of oligomeric non-collagenous extracellular matrix proteins that are assumed to act as adapter molecules connecting other proteins and proteoglycans in the extracellular matrix (PMID: 17513098). Four matrilins (matrilin-1, -2, -3, and -4) have been identified. They all share a structure made up of von Willebrand factor A domains, EGF-like domains and a coiled-coil alpha-helical module (PMID: 18386166). Matrilin-1 and matrilin-3 are expressed mainly in cartilage, while matrilin-2 and matrilin-4 show broader tissue distribution. Matrilin-2 is the largest member of the family. It incorporates into loose and dense connective tissue and becomes associated with some basement membranes (PMID: 17513098).

Protocols

Product Specific Protocols
WB protocol for Matrilin 2 antibody 24064-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
zebrafishWB

Sci Adv

A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations.

Authors - Ranjay Jayadev
  • KD Validated
mouseWB,IF

J Mol Med (Berl)

Valproic acid modulates collagen architecture in the postoperative conjunctival scar.

Authors - Li-Fong Seet