MCOLN1 Recombinant antibody, PBS Only

• 

  WB analysis of rat kidney using 85339-1-RR (same clone as 85339-1-PBS)

  rat kidney tissue were subjected to SDS PAGE followed by western blot with 85339-1-RR (MCOLN1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85339-1-PBS in a different storage buffer formulation.

MCOLN1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85339-1-PBS

Clone No.242586D4

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Indirect ELISA

Synonyms

MST080, MLIV, ML4, ML1, MG 2

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Product Information

85339-1-PBS targets MCOLN1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: MCOLN1 fusion protein Ag7493
• Full Name: mucolipin 1
• Calculated Molecular Weight: 65 kDa
• Observed Molecular Weight: 60 kDa
• GenBank Accession Number: BC005149
• Gene Symbol: MCOLN1
• Gene ID (NCBI): 57192
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9GZU1
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

MCOLN1, also named MLIV, ML4, MG-2, and Mucolipidin, belongs to the transient receptor (TC 1.A.4) family, Polycystin subfamily, and MCOLN1 sub-subfamily. It is playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. MCOLN1 may play a major role in Ca2+ transport regulating lysosomal exocytosis. It is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration, and strabismus.