Recombinant Mouse Butyrylcholinesterase protein (rFc Tag)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
rFc Tag
Activity
not tested
Cat no : Eg2899
Validation Data Gallery
Product Information
Purity | >90 %, SDS-PAGE |
Endotoxin | <0.1 EU/μg protein, LAL method |
Activity |
Not tested |
Expression | HEK293-derived Mouse Butyrylcholinesterase protein His28-Leu603 (Accession# Q03311) with a rabbit IgG Fc tag at the C-terminus. |
GeneID | 12038 |
Accession | Q03311 |
PredictedSize | 91.3 kDa |
SDS-PAGE | 90-120 kDa, reducing (R) conditions |
Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Butyrylcholinesterase (BChE) is an ester hydrolase that hydrolyzes certain short-acting neuromuscular blockers such as succinylcholine and mivacurium chloride. BChE is mainly produced in the liver and distributed through out all tissues. BChE is associated with lipid metabolism.
References:
1.Brimijoin S. et al. (2016) Chem Biol Interact. 259(Pt B):271-275. 2.Lins Alves LK. et al. (2022) Chem Biol Interact. 367:110136. 3.Gok M. et al. (2023) Biochimie. 204:127-135. 4.Zeng J. et al. (2024) Medicine (Baltimore). 103(40):e39976.