NDEL1 Polyclonal antibody

NDEL1 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 17262-1-AP


EOPA, MITAP1, Mitosin associated protein 1, NDEL1, NUDEL, Protein Nudel

Tested Applications

Positive WB detected inhuman brain tissue, HepG2 cells
Positive IP detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

17262-1-AP targets NDEL1 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen NDEL1 fusion protein Ag10975
Full Name nudE nuclear distribution gene E homolog (A. nidulans)-like 1
Calculated molecular weight 345 aa, 38 kDa, 41 kDa
Observed molecular weight 38-42 kDa
GenBank accession numberBC026101
Gene symbol NDEL1
Gene ID (NCBI) 81565
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Nuclear distribution factor E-homolog 1 (NDE1), NDE-like 1 (NDEL1), and Lissencephaly 1 (LIS1) together involve in essential neurodevelopmental processes, including neuronal precursor proliferation and differentiation, neurite outgrowth, and neuronal migration. All three bind directly to Disrupted in Schizophrenia 1 (DISC1), a scaffold protein critical to neuronal proliferation, integration, migration, and synaptic function within the developing and adult brain.[PMID: 18469341] Nuclear distribution element-like 1 (NDEL1) was firstly identified as a regulator of the cytoskeleton in microtubule and intermediate fliament dynamics and microtubule-based transport [PMID:21948775]. It is required for organization of the cellular microtubule array and microtubule anchoring at the centrosome, which is in part by targeting the microtubule severing protein KATNA1 to the centrosome[PMID:15728732].


Product Specific Protocols
WB protocol for NDEL1 antibody 17262-1-APDownload protocol
IP protocol for NDEL1 antibody 17262-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



J Cell Biol

Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis.

Authors - Sumigray Kaelyn D KD
mouseIP, WB


Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis.

Authors - Youngsik Woo

Sci Rep

Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration.

Authors - Ji-Ho Hong

Ann Neurol

Extraciliary roles of the ciliopathy protein JBTS17 in mitosis and neurogenesis.

Authors - Hyowon Hong

Proc Natl Acad Sci U S A

Gcap14 is a microtubule plus-end-tracking protein coordinating microtubule-actin crosstalk during neurodevelopment

Authors - Dong Jin Mun