OBFC2A Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 16719-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 36 μg/150 μl

Choose size:

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Species specificity:
human, mouse, rat

Positive WB detected in:
COLO 320 cells

Recommended dilution:
WB : 1:500-1:1000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
oligonucleotide/oligosaccharide-binding fold containing 2A

Calculated molecular weight:
124aa,14 kDa

Observed molecular weight:
22kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
OBFC2A

Synonyms
OBFC2A, DKFZp667M1322, hSSB2, SSB2, Sensor of ssDNA subunit B2
Background

Single-stranded DNA (ssDNA)-binding proteins (SSBs) are ubiquitous and essential for a variety of DNA metabolic processes, including recombination, replication, and detection and repair of damage. SSBs have multiple roles in binding and sequestering ssDNA, detecting DNA damage, stimulating nucleases, helicases and strand-exchange proteins, activating transcription and mediating protein-protein interactions [PMID:18449195] Human single-stranded DNA-binding protein 1 (hSSB1), encoded by OBFC2B, is characterized as an essential factor for the initiation of DNA damage checkpoints and the maintenance of genomic stability [PMID:22940690].


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