PAQR7 Polyclonal antibody

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  WB analysis using 24966-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 24966-1-AP (PAQR7 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

PAQR7 Polyclonal Antibody for WB, ELISA

Cat No. 24966-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Synonyms

mSR, MRPA, MPRA, mPR alpha, Membrane progesterone receptor alpha

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Tested Applications

• Positive WB detected in: HEK-293 cells, HeLa cells, SW480 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

24966-1-AP targets PAQR7 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PAQR7 fusion protein Ag21655
• Full Name: progestin and adipoQ receptor family member VII
• Calculated Molecular Weight: 346 aa, 40 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: BC034015
• Gene Symbol: PAQR7
• Gene ID (NCBI): 164091
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q86WK9
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Progestin and adipoQ receptor 7 (PAQR7), also called membrane P4 receptor α (mPRα), is a membrane protein with seven transmembrane domains, similar to G protein-coupled receptors (PMID: 34217103). Studies have shown that PAQR7 has important physiological functions in various reproductive tissues (PMID: 12601167). In addition, PAQR7 participates in the antimitotic action of P4 in human GCs and luteal cells, and P4's ability to suppress entry into the cell cycle was dependent on PAQR7 but not nuclear progesterone receptor (PGR) (PMID: 26203174).