Product Information
84593-1-PBS targets PAR3 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | coagulation factor II (thrombin) receptor-like 2 |
Calculated Molecular Weight | 374 aa, 43 kDa |
Observed Molecular Weight | 45 kDa |
GenBank Accession Number | BC093648 |
Gene Symbol | PAR3 |
Gene ID (NCBI) | 2151 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
UNIPROT ID | O00254 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
PAR3 is a crucial protein involved in the establishment and maintenance of cell polarity across various species. It plays a significant role in organizing cellular structures and functions, particularly in epithelial and neuronal cells. PAR3 has been implicated in various aspects of cancer biology. It can act as a tumor suppressor in epithelial cancers, and its expression or mutations have been associated with the progression and behavior of glioblastoma, pancreatic cancer, and other malignancies.