PAX4 Polyclonal antibody

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  IF Staining of A549 using 13018-2-AP

  Immunofluorescent analysis of A549 cells, using PAX4 antibody 13018-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

PAX4 Polyclonal Antibody for IF, ELISA

Cat No. 13018-2-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF, ELISA

Synonyms

KPD, MODY9, paired box 4, Paired box protein Pax 4, PAX4

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Product Information

13018-2-AP targets PAX4 in IF, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PAX4 fusion protein Ag4111
• Full Name: paired box 4
• Calculated Molecular Weight: 343 aa, 37 kDa
• GenBank Accession Number: BC074761
• Gene Symbol: PAX4
• Gene ID (NCBI): 5078
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O43316
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PAX4, a paired-box transcription factor, is a key regulator of pancreatic islet cell growth and differentiation. Differentiation of endoderm-derived endocrine pancreas is mediated through PAX4 and PAX6. PAX4 may act as a PAX6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. PAX4 has the potential to function as a tumor suppressor in human melanoma.