PI3 Kinase p55 Gamma Polyclonal antibody
PI3 Kinase p55 Gamma Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 55036-1-AP
Synonyms
Validation Data Gallery
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 6 publications below |
Product Information
55036-1-AP targets PI3 Kinase p55 Gamma in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide |
| Full Name | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| Calculated Molecular Weight | 54 kDa |
| GenBank Accession Number | NM_003629 |
| Gene Symbol | PIK3R3 |
| Gene ID (NCBI) | 8503 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
PIK3R3, also named as p55PIK, belongs to the PI3K p85 subunit family. It binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During INS stimulation, it also binds to IRS-1. It is a component of a heterodimer of p110 (catalytic) and p55 (regulatory) subunits. The antibody is specific to PIK3R3.
Publications
| Species | Application | Title |
|---|---|---|
RNA Biol MicroRNA-432 targeting E2F3 and P55PIK inhibits myogenesis through PI3K/AKT/mTOR signaling pathway. | ||
Mol Biol Cell MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway. | ||
Tumour Biol MiR-511 inhibits growth and metastasis of human hepatocellular carcinoma cells by targeting PIK3R3. | ||
Transl Androl Urol Study on the mechanism of aging-related erectile dysfunction based on bioinformatics and experimental verification | ||
Tumour Biol Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics. | ||
Andrology Saxagliptin alleviates erectile dysfunction through increasing SDF-1 in diabetes mellitus |
