|Positive WB detected in||HepG2 cells, HeLa cells|
|Positive IF detected in||Hela cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Immunofluorescence (IF)||IF : 1:10-1:100|
|Sample-dependent, check data in validation data gallery|
17894-1-AP targets VPS15 in WB, IP, IF, CoIP applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||VPS15 fusion protein Ag12221|
|Full Name||phosphoinositide-3-kinase, regulatory subunit 4|
|Calculated molecular weight||1358 aa, 153 kDa|
|Observed molecular weight||150 kDa|
|GenBank accession number||BC110318|
|Gene ID (NCBI)||30849|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
PIK3R4(phosphoinositide 3-kinase regulatory subunit 4) is also named as PI3-kinase p150 subunit and belongs to the Ser/Thr protein kinase family. It is a regulatory subunit of the PI3K complex and may regulate membrane trafficking late in the endocytic pathway. This protein can be probably autophosphorylated(PMID:19369195).
Exp Ther Med
Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats.
Targeting AR-Beclin 1 Complex-Modulated Growth Factor Signaling Increases the Antiandrogen-Enzalutamide Sensitivity to Better Suppress the Castration-Resistant Prostate Cancer Growth.
J Hazard Mater
Nano-graphene oxide depresses neurotransmission by blocking retrograde transport of mitochondria.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.