PLXNB1 Polyclonal antibody

PLXNB1 Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse and More (1)





Cat no : 23795-1-AP


KIAA0407, plexin B1, PLXN5, PLXNB1, Semaphorin receptor SEP, SEP

Tested Applications

Positive WB detected inmouse brain tissue
Positive IHC detected inhuman kidney tissue, human brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:200-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 23795-1-AP is PLXNB1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PLXNB1 fusion protein Ag20719
Full Name plexin B1
Calculated Molecular Weight 2135 aa, 232 kDa
Observed Molecular Weight 210 kDa
GenBank Accession NumberBC146793
Gene Symbol PLXNB1
Gene ID (NCBI) 5364
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Semaphorins, originally identified as axon guidance molecules, have also been implicated in angiogenesis, immunoregulation, and cancer (PMID: 16584533). Plexins are main receptors for semaphorins and are thought to control many of the functional effects of semaphorins. PLXNB1 is one of the three plexin-B family members. It is a high-affinity receptor for semaphorin 4D (SEMA4D). Interaction of SEMA4D and PLXNB1 has important physiologic effects in the immune and nervous systems, and is also involved in tumor progression, especially in tumor angiogenesis (PMID: 20858260).


Product Specific Protocols
WB protocol for PLXNB1 antibody 23795-1-APDownload protocol
IHC protocol for PLXNB1 antibody 23795-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Cancer Immunol Res

Semaphorin4D Inhibition Improves Response to Immune-Checkpoint Blockade via Attenuation of MDSC Recruitment and Function.

Authors - Paul E Clavijo

J Transl Med

SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling.

Authors - Lu Liu

Ann Transl Med

Proteomics and metabolomics of raw rhubarb and wine-processed rhubarb in the treatment of rats with intracerebral hemorrhage.

Authors - Kun Wang

J Neuroendocrinol

PLXNB1 mutations in the etiology of idiopathic hypogonadotropic hypogonadism.

Authors - Bradley A Welch

Ann Transl Med

Methylation-based epigenetic studies and gene integration analysis of preeclampsia

Authors - Lei Jiang


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Boyan (Verified Customer) (10-04-2021)

calculated size 230 kd. this antibody recognized major bands at 35, 30 kd.

  • Applications: Western Blot