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  • KD/KO Validated

PPARD Monoclonal antibody

PPARD Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat, pig and More (1)

Applications

WB, ChIP, ELISA

Conjugate

Unconjugated

CloneNo.

1B10E1

Cat no : 60193-1-Ig

Synonyms

FAAR, NR1C2, NUC1, NUCI, NUCII, Nuclear hormone receptor 1, PPAR beta, PPAR delta, PPARB, PPARD



Tested Applications

Positive WB detected inHeLa cells, A549 cells, pig adipose tissue, Jurkat cells, K-562 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

60193-1-Ig targets PPARD in WB, ChIP, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Reactivity human, mouse, rat, pig
Cited Reactivityhuman, mouse, rat, zebrafish
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen PPARD fusion protein Ag16770
Full Name peroxisome proliferator-activated receptor delta
Calculated Molecular Weight 50 kDa
Observed Molecular Weight 54 kDa
GenBank Accession NumberBC002715
Gene Symbol PPARD
Gene ID (NCBI) 5467
RRIDAB_10896827
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Peroxisome proliferator-activator receptor delta(PPARD), a ligand-activated transcription factor, belongs to the PPARs family, which get its name for their chemicals that induce proliferation of peroxisomes, organelles that contributes to the oxidation of fatty acids. PPARD is a receptor for peroxisome proliferator and once activated by a ligand, it binds to and activates the promoter elements of target genes, such as acylCoA oxidase gene. But it act as a repressor for the NPC1L1 gene.

Protocols

Product Specific Protocols
WB protocol for PPARD antibody 60193-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Nat Commun

A proteomics landscape of circadian clock in mouse liver.

Authors - Yunzhi Wang
mouseWB

Liver Int

PPARβ/δ activation protects against hepatic ischaemia-reperfusion injury

Authors - Baolin Qian
  • KD Validated
mouseWB

Am J Physiol Endocrinol Metab

Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice

Authors - Alyssa Charrier
mouseWB

Front Aging Neurosci

A tau fragment links depressive-like behaviors and cognitive declines in Alzheimer's disease mouse models through attenuating mitochondrial function

Authors - Yamei Wang
ratWB

J Ethnopharmacol

Anchang Yuyang Decoction inhibits experimental colitis-related carcinogenesis by regulating PPAR signaling pathway and affecting metabolic homeostasis of host and microbiota

Authors - Xiunan Wei
humanWB,ChIP

Adv Sci (Weinh)

The Loss of an Orphan Nuclear Receptor NR2E3 Augments Wnt/β-catenin Signaling via Epigenetic Dysregulation that Enhances Sp1-β catenin-p300 Interactions in Hepatocellular Carcinoma

Authors - Yuet-Kin Leung