PPEF2 Polyclonal antibody, PBS Only

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  WB analysis using 31543-1-AP (same clone as 31543-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31543-1-AP (PPEF2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31543-1-PBS in a different storage buffer formulation.

PPEF2 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31543-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

31543-1-PBS targets PPEF2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PPEF2 fusion protein Ag35922
• Full Name: protein phosphatase, EF-hand calcium binding domain 2
• Calculated Molecular Weight: 86kDa
• Observed Molecular Weight: 69 kDa
• GenBank Accession Number: NM_006239
• Gene Symbol: PPEF2
• Gene ID (NCBI): 5470
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: O14830
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Pprotein phosphatase with EF-hand domain 2 (PPEF2), also known as PPP7CB, is a member of the serine/threonine protein phosphatase with EF-hand motif family. PPEF2 can dephosphorylate ubiquitin and suppress PINK1-dependent mitophagy. PPEF2 functions to suppress mitochondrial quality control on a cellular level through dephosphorylation of p-S65 ubiquitin. PPEF2 exists 2 isoforms produced by alternative splicing with a molecular weight of 86 kDa (PPEF-2(L)) and 69 kDa (PPEF-2(S)).