Product Information
83231-3-PBS targets PPP1R1A as part of a matched antibody pair:
MP00197-1: 83231-3-PBS capture and 83231-1-PBS detection (validated in Cytometric bead array)
MP00197-2: 83231-3-PBS capture and 83231-2-PBS detection (validated in Cytometric bead array)
Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | PPP1R1A fusion protein Ag3128 Predict reactive species |
| Full Name | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| Calculated Molecular Weight | 171 aa, 19 kDa |
| GenBank Accession Number | BC022470 |
| Gene Symbol | PPP1R1A |
| Gene ID (NCBI) | 5502 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q13522 |
| Storage Buffer | PBS only, pH 7.3. |
| Storage Conditions | Store at -80°C. |
Background Information
PPP1R1A, also known as protein phosphatase 1 regulatory subunit 1A, is a gene that plays a crucial role in regulating the activity of protein phosphatase 1 (PP1). As an inhibitor, PPP1R1A binds to PP1, preventing the dephosphorylation of PP1 to other proteins. This gene influences a broad range of cellular functions by maintaining the phosphorylation of specific proteins and is directly involved in glycogen metabolism, cardiac contractility, and cell proliferation. PPP1R1A is considered a key factor in regulating cellular signaling and physiological homeostasis. .
