|Positive WB detected in||NIH/3T3 cells, C6 cells, mouse brain tissue, rat brain tissue|
|Positive IP detected in||mouse brain tissue|
|Positive IF detected in||Saos-2 cells, A431 cells, HeLa cells|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
14188-1-AP targets PKC Delta in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||PKC Delta fusion protein Ag5473|
|Full Name||protein kinase C, delta|
|Calculated molecular weight||78 kDa|
|Observed molecular weight||70-80 kDa|
|GenBank accession number||BC043350|
|Gene ID (NCBI)||5580|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
PKC Delta is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrom.
Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms.
Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy.
J Biol Chem
Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double strand break repair.
Theaflavin-3,3'-di-gallate represses prostate cancer by activating the PKCδ/aSMase signaling pathway through a 67 kDa laminin receptor.
Chem Biol Interact
ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.
PKCδ regulates chromatin remodeling and DNA repair through SIRT6
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Wassim (Verified Customer) (04-23-2019)
This antibody picks a band ~76 KDa in mouse kidney tubular cells lysed in RIPA buffer.
Angela (Verified Customer) (12-17-2018)
Lanes are as follows: 1 SCR control2 pkcd shrna13 pkcd shrna24 pkcd shrna35 50uM etoposide 18hr6 untreated control