|Positive WB detected in||NIH/3T3 cells, C6 cells, mouse brain tissue, rat brain tissue|
|Positive IP detected in||mouse brain tissue|
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB|
|Sample-dependent, check data in validation data gallery|
14188-1-AP targets PKC Delta in WB, IP, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||PKC Delta fusion protein Ag5473|
|Full Name||protein kinase C, delta|
|Calculated molecular weight||78 kDa|
|Observed molecular weight||70-80 kDa|
|GenBank accession number||BC043350|
|Gene ID (NCBI)||5580|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
PKC Delta is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrom.
Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms.
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J Biol Chem
Tyrosine kinase inhibitors protect the salivary gland from radiation damage by increasing DNA double strand break repair.
Theaflavin-3,3'-di-gallate represses prostate cancer by activating the PKCδ/aSMase signaling pathway through a 67 kDa laminin receptor.
Chem Biol Interact
ZCL-082, a boron-containing compound, induces apoptosis of non-Hodgkin's lymphoma via targeting p90 ribosomal S6 kinase 1/NF-κB signaling pathway.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Wassim (Verified Customer) (04-23-2019)
This antibody picks a band ~76 KDa in mouse kidney tubular cells lysed in RIPA buffer.
Angela (Verified Customer) (12-17-2018)
Lanes are as follows: 1 SCR control2 pkcd shrna13 pkcd shrna24 pkcd shrna35 50uM etoposide 18hr6 untreated control