- Featured Product
- KD/KO Validated
PSD95-Specific,DLG4 Polyclonal antibody
PSD95-Specific,DLG4 Polyclonal Antibody for IHC, IP, WB,ELISA
Cat no : 20665-1-AP
|Positive WB detected in||mouse brain tissue, mouse cerebellum tissue, HeLa cells, rat brain tissue|
|Positive IP detected in||mouse brain tissue|
|Positive IHC detected in||mouse brain tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:1000-1:6000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:250-1:1000|
|Sample-dependent, check data in validation data gallery|
20665-1-AP targets PSD95-Specific,DLG4 in WB, IP, IHC, IF,ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||hamster, human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Full Name||discs, large homolog 4 (Drosophila)|
|Calculated molecular weight||85 kDa|
|Observed molecular weight||90-95 kDa|
|GenBank accession number||NM_001365|
|Gene ID (NCBI)||1742|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene. PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation. Observed MW of PSD95 is 90-95 kDa due to phosphorylation (PMID: 20682303).
|Product Specific Protocols|
|WB protocol for PSD95-Specific,DLG4 antibody 20665-1-AP||Download protocol|
|IHC protocol for PSD95-Specific,DLG4 antibody 20665-1-AP||Download protocol|
|IP protocol for PSD95-Specific,DLG4 antibody 20665-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Neural Regen Res
Int J Mol Sci
J Cell Physiol
The overexpression of GRASP might inhibit cell proliferation and invasion in hepatocellular carcinoma.
CAMK2-dependent signaling in neurons is essential for survival.
J Neurosci Res
Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway.