PSD95-Specific,DLG4 Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 20665-1-AP

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Freight/Packing

Con: 28 μg/150 μl

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Species specificity:
human, mouse, rat, hamster, hamsters

Positive WB detected in:
mouse brain tissue,rat brain tissue

Positive IP detected in:
mouse brain tissue

Positive IHC detected in:
rat brain tissue, mouse brain tissue, rat brain tissue

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IHC : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
discs, large homolog 4 (Drosophila)

Calculated molecular weight:
85 kDa

Observed molecular weight:
90-95 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
DLG4

Synonyms
Disks large homolog 4, DLG4, FLJ97752, FLJ98574, PSD 95, PSD95, SAP 90, SAP90, Synapse associated protein 90
Background

PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene. PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation. Observed MW of PSD95 is 90-95 kDa due to phosphorylation (PMID: 20682303).


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