Phospho-LATS1 (Thr1079) Polyclonal antibody

Phospho-LATS1 (Thr1079) Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


Human and More (1)





Cat no : 28998-1-AP


h warts, LATS1, Phospho-LATS1 (Thr1079), WARTS, WARTS protein kinase, wts

Tested Applications

Positive WB detected inCalyculin A treated HeLa cells

Recommended dilution

Western Blot (WB)WB : 1:5000-1:50000
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 3 publications below

Product Information

28998-1-AP targets Phospho-LATS1 (Thr1079) in WB, ELISA applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivityhuman
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name LATS, large tumor suppressor, homolog 1 (Drosophila)
Calculated molecular weight 15 kDa, 127 kDa
Observed molecular weight140-150 kDa
GenBank accession numberBC015665
Gene symbol LATS1
Gene ID (NCBI) 9113
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The large tumour suppressor 1 (LATS1) acting as a tumour suppressor is a serine/threonine kinase of the AGC kinase family and is found to be down-regulated in various types of human cancers. Recently, LATS1 has been identified as a central player of the emerging tumour suppressive Hippo signaling pathway. In this pathway, the MST1/2 kinase phosphorylates activates LATS1/2 which, together with its co-factor MOB1, subsequently phosphorylates and inhibits the YAP transcriptional factor by preventing them from translocating to the nucleus. The antibody also detects the phosphorylated at Thr1041 of the LATS2. (PMID: 32460168, PMID: 30219064,PMID: 31792377)


Product Specific Protocols
WB protocol for Phospho-LATS1 (Thr1079) antibody 28998-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Int J Biol Sci

S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development

Authors - Yifang Hu

Cell Mol Biol Lett

KIAA1429-mediated m6A modification of CHST11 promotes progression of diffuse large B-cell lymphoma by regulating Hippo-YAP pathway

Authors - Xiaomin Chen

Cell Death Dis

PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling

Authors - Hualin Chen