|Positive WB detected in||NIH/3T3 cells, λ phosphatase treated NIH/3T3 cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
28955-1-AP targets Phospho-MEK2 (Thr394) in WB, ELISA applications and shows reactivity with Human, Mouse samples.
|Tested Reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||mitogen-activated protein kinase kinase 2|
|Calculated molecular weight||44 kDa|
|Observed molecular weight||44 kDa|
|GenBank accession number||BC018645|
|Gene ID (NCBI)||5605|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Aliquoting is unnecessary for -20oC storage.|
MEK2(MAPK/ERK kinase 2) is also named as MAP2K2, MKK2, PRKMK2 and belongs to the MAP kinase kinase subfamily. MAPKK is itself dependent on Ser/Thr phosphorylation for activity catalyzed by MAP kinase kinase kinases (RAF or MEKK1). MEK1 and MEK2 are closely related, dual-specificity tyrosine/threonine protein kinases found in the Ras/Raf/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathway.