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CD138/Syndecan-1 Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 10593-1-AP

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Con: 38 μg/150 μl

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Tested Applications

Applications:
WB, IP, IHC, IF, ELISA
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Images See all

CD138/Syndecan-1 Antibody WB Raji cells 10593-1-AP

Raji cells were subjected to SDS PAGE followed by western blot with 10593-1-AP(CD138/Syndecan-1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours

CD138/Syndecan-1 Antibody IHC human tonsillitis tissue 10593-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 10593-1-AP (CD138/Syndecan-1 antibody) at dilution of 1:1600 (under 10x lens) heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

CD138/Syndecan-1 Antibody IHC human tonsillitis tissue 10593-1-AP

Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 10593-1-AP (CD138/Syndecan-1 antibody) at dilution of 1:1600 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Species specificity:
human, mouse, rat
Positive WB detected in:
Raji cells, HeLa cells
Positive IHC detected in:
human tonsillitis tissue, human ovary tumor tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:500-1:1000
IHC : 1:800-1:3200
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
CD138/Syndecan-1 fusion protein Ag0823
Full name:
syndecan 1
Calculated molecular weight:
32.5 kDa
Observed molecular weight:
60-100 kDa
GenBank accession number:
BC008765
Gene ID (NCBI):
6382
Gene symbol
SDC1
Synonyms
CD138, SDC, SDC1, SYND1, syndecan, syndecan 1

Background

CD138, also named as Syndecan-1 (SDC1), is an integral membrane protein. It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. CD138 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas. CD138 has a calculated molecular weight of 32.5 kDa, the apparent molecular weight is higher due to extensive glycosylation.


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