SIRT5 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 15122-1-AP

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Freight/Packing

Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, mouse liver tissue

Positive IP detected in:
mouse liver tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)

Calculated molecular weight:
34 kDa

Observed molecular weight:
33 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SIRT5

Synonyms
FLJ36950, SIR2 like protein 5, SIR2L5, SIRT5
Background

SIRT5, a member fo sirtuin family that is a mitochondrial matrix NAD(+)-dependent deacetylase and mono-ADP-ribosyltransferases. Sirtuins play important role in various cellular processed, such as aging, gene silencing and metabolism. SIRT5 mainly locates in . It is an efficient protein lysine desuccinylase and demalonylase. During prolonged fasting, it can activate CPS1, the committed and regulated enzyme of the urea cycle, and contribute to the regulation of blood ammonia levels.


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