SMCR7L/MID51 Antibody 18 Publications

Rabbit Polyclonal| Catalog number: 20164-1-AP

Featured Product KD/KO validated

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Con: 36 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HT-1080 cells, mouse heart tissue, mouse testis tissue, NIH/3T3 cells, rat liver tissue, rat testis tissue

Positive IP detected in:
RAW 264.7 cells

Positive IF detected in:
Hela cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
Smith-Magenis syndrome chromosome region, candidate 7-like

Calculated molecular weight:
463aa,51 kDa

Observed molecular weight:
48-51 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

HSU79252, MID51, MIEF1, SMCR7L

Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa (also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.

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