SOX2 Antibody 6 Publications

Rabbit Polyclonal| Catalog number: 20118-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 50 μg/150 μl

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Species specificity:
human, mouse, rat, zebrafish

Positive WB detected in:
mouse brain tissue, Transfected HEK-293 cells

Positive IHC detected in:
mouse embryo tissue

Positive IF detected in:
mouse embryo tissue

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
SRY (sex determining region Y)-box 2

Calculated molecular weight:
34 kDa

Observed molecular weight:
34-40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
SOX2

Synonyms
ANOP3, MCOPS3, SOX2, Transcription factor SOX 2
Background

Sox2, also known as SRY (sex determining region Y)-box 2, is a transcription factor essential for maintaining self-renewal of undifferentiated ES cells and is one of the key transcription factors used to reprogram mouse and human fibroblasts to a pluripotent state. Sox2 expressed in undifferentiated pluripotent stem cells and germ cells during development. Affinity purified rabbit anti-Sox2 antibody can be used to demonstrate pluripotency of ES and iPS cells. This antibody is a rabbit polyclonal antibody raised against an internal region of human SOX2. a rare undiferentiated cell population that is intermingled with the Bergmann glia of the adult murine cerebellar cortex, expresses the stem cell markers Sox2 and Nestin, and lacks markers of glial or neuronal diferentiation. Sox2-expressing neural stem cells in the subgranular zone (SGZ) , a well-known stem cell niche of the adult brain.

SOX2 Rabbit Polyclonal antibody

Ryan MacDonald, 02-15-2018

Applications
Immunohistochemistry,
Lot Number
00012908

Primary Antibody Dilution
1:200
Secondary Antibody Dilution
1:1000

Cell/Tissue Type
Zebrafish retina 5dpf


NaCit antigen retrieval ph=6

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