Stanniocalcin 2 Polyclonal antibody

Stanniocalcin 2 Polyclonal Antibody for IF, IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 10314-1-AP

Synonyms

stanniocalcin 2, Stanniocalcin related protein, STC 2, STC related protein, STC2, STCRP



Tested Applications

Positive IHC detected inhuman renal cell carcinoma tissue, human lung cancer tissue, human colon cancer tissue, human kidney tissue, human stomach cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inU2OS cells

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

10314-1-AP targets Stanniocalcin 2 in WB, IHC, IF,ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Stanniocalcin 2 fusion protein Ag0359
Full Name stanniocalcin 2
Calculated molecular weight 33 kDa
GenBank accession numberBC000658
Gene symbol STC2
Gene ID (NCBI) 8614
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Stanniocalcin (STC) is a family of secreted glycoprotein hormones that originally discovered in the corpuscles of Stannius, an endocrine gland of fish. STC1 and STC2, two homologues of STC family, are reported to involve in calcium and phosphate homeostasis. It is expressed in a wide variety of tissues such as kidney, spleen, heart, and pancreas. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. STC2 overexpression could promote tumor cell proliferation, invasion and metastasis in prostate cancer, ovarian cancer or neuroblastoma. STC2 is also vital for cytoprotective properties when exposed to ER stress and hypoxia.

Protocols

Product Specific Protocols
IHC protocol for Stanniocalcin 2 antibody 10314-1-APDownload protocol
IF protocol for Stanniocalcin 2 antibody 10314-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

Endocr Relat Cancer

Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs.

Authors - Hiroki Ueda
humanIHC

Cancer Biomark

Evaluation of protein expression pattern of stanniocalcin 2, insulin-like growth factor-binding protein 7, inhibin beta A and four and a half LIM domains 1 in esophageal squamous cell carcinoma.

Authors - Kashyap Manoj Kumar MK
humanIHC

Oncol Rep

Clinical significance of stanniocalcin 2 expression as a predictor of tumor progression in gastric cancer.

Authors - Arigami Takaaki T
humanIHC

Int J Cancer

Additive effect of the AZGP1, PIP, S100A8, and UBE2C molecular biomarkers improves outcome prediction in breast carcinoma.

Authors - Parris Toshima Z TZ
humanIHC

Genomics Proteomics Bioinformatics

miRNA-mRNA Regulatory Network and Factors Associated with Prediction of Prognosis in Hepatocellular Carcinoma.

Authors - Bo Hu
humanWB,IHC

Eur Urol

Identification of stanniocalcin 2 as prognostic marker in renal cell carcinoma.

Authors - Meyer Hellmuth-A HA