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STMN2 Polyclonal antibody
STMN2 Polyclonal Antibody for IF, IHC, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat and More (1)
WB, IP, IHC, IF, ELISA
Cat no : 10586-1-AP
|Positive WB detected in||mouse brain tissue|
|Positive IP detected in||mouse brain tissue|
|Positive IHC detected in||mouse brain tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||SH-SY5Y cells, mouse brain tissue|
|Western Blot (WB)||WB : 1:1000-1:6000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:10-1:100|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 1 publications below|
|WB||See 10 publications below|
|IHC||See 4 publications below|
|IF||See 3 publications below|
10586-1-AP targets STMN2 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||STMN2 fusion protein Ag0929|
|Full Name||stathmin-like 2|
|Calculated molecular weight||21 kDa|
|Observed molecular weight||18-21 kDa|
|GenBank accession number||BC006302|
|Gene ID (NCBI)||11075|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Stathmin-2 (encoded by STMN2), a member of the stathmin family of proteins, encodes a phosphoprotein that has an important role in microtubule dynamics. The STMN2 protein promotes microtubule dynamics in axonal growth cones , and is thought to play an important role in neurite outgrowth. STMN2 protein is localized in both Golgi and cytosolic compartments. Its expression appears modulated in osteoblasts by nerve growth factor, dexamethasone or RhoA kinase inhibitor Y-27632 which are known effectors of osteogenesis. (PMID: 33841129, PMID: 18611392)
|Product Specific Protocols|
|WB protocol for STMN2 antibody 10586-1-AP||Download protocol|
|IHC protocol for STMN2 antibody 10586-1-AP||Download protocol|
|IF protocol for STMN2 antibody 10586-1-AP||Download protocol|
|IP protocol for STMN2 antibody 10586-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Molecular substrates of altered axonal growth and brain connectivity in a mouse model of schizophrenia.
Proc Natl Acad Sci U S A
SCG10 is a JNK target in the axonal degeneration pathway.
J Cell Biol
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration.
J Cell Biol
A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.
Retrograde Ret signaling controls sensory pioneer axon outgrowth.
CNGA3: a target of spinal nitric oxide/cGMP signaling and modulator of inflammatory pain hypersensitivity.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Tatyana (Verified Customer) (01-09-2023)
Good signal both in WB and ICC on neuroblastoma cells (neuronal cell line). Was used 1:1000 in both applications. Gave some non-specific bands in WB. ICC - 5% goat serum / PBST WB - 4% milk / TBST