• Featured Product
  • KD/KO Validated

Transgelin 2 Polyclonal antibody

Transgelin 2 Polyclonal Antibody for WB, IF, ELISA

Host / Isotype

Rabbit / IgG


human and More (1)





Cat no : 10234-2-AP


SM22 beta, SM22beta, TAGLN2, Transgelin 2

Tested Applications

Positive WB detected inhuman heart tissue, HEK-293 cells, T-47D cells
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunofluorescence (IF)IF : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10234-2-AP targets Transgelin 2 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Transgelin 2 fusion protein Ag0337
Full Name transgelin 2
Calculated Molecular Weight 199 aa, 22 kDa
Observed Molecular Weight 22 kDa
GenBank Accession NumberBC002616
Gene Symbol Transgelin-2/TAGLN2
Gene ID (NCBI) 8407
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The transgelin family is a group of proteins that belong to 22 kDa actin-related corpnin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22 alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgenlin 2 protein. It may cross react with other two transgelins based on the sequence similarity.


Product Specific Protocols
WB protocol for Transgelin 2 antibody 10234-2-APDownload protocol
IHC protocol for Transgelin 2 antibody 10234-2-APDownload protocol
IF protocol for Transgelin 2 antibody 10234-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Mol Cell Proteomics

Comparative Tissue Proteomics of Microdissected Specimens Reveals Novel Candidate Biomarkers of Bladder Cancer.

Authors - Chien-Lun Chen

J Proteome Res

Identification of vascular breast tumor markers by laser capture microdissection and label-free LC-MS.

Authors - Hill Jennifer J JJ

J Proteome Res

Tissue proteomics reveals differential and compartment-specific expression of the homologs transgelin and transgelin-2 in lung adenocarcinoma and its stroma.

Authors - Rho Jung-Hyun JH

J Proteome Res

Post-translational modifications and protein-specific isoforms in endometriosis revealed by 2D DIGE.

Authors - Stephens Andrew N AN

Front Oncol

Prognosis Analysis and Validation of m6A Signature and Tumor Immune Microenvironment in Glioma.

Authors - Shaojian Lin

Cancer Sci

Hypoxia-inducible transgelin 2 selects epithelial-to-mesenchymal transition and γ-radiation-resistant subtypes by focal adhesion kinase-associated insulin-like growth factor 1 receptor activation in non-small-cell lung cancer cells.

Authors - In-Gyu Kim
  • KD Validated


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Joleen (Verified Customer) (06-16-2019)

It recognizes transgelin (prominent lower band) and some other bands, albeit much more weakly.

  • Applications: Western Blot,
  • Primary Antibody Dilution: 1:1k
  • Cell Tissue Type: MDCK GII
Transgelin 2 Antibody Western Blot, validation (1:1k dilution) in MDCK GII (Cat no:10234-2-AP)