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TGF beta 2-Specific Polyclonal antibody
TGF beta 2-Specific Polyclonal Antibody for IF, IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
human, mouse and More (2)
WB, IHC, IF, ELISA
Cat no : 19999-1-AP
Validation Data Gallery
|Positive WB detected in||HeLa cells, K-562 cells, mouse lung tissue, MCF-7 cells|
|Positive IHC detected in||human breast cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HeLa cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 1 publications below|
|WB||See 30 publications below|
|IHC||See 8 publications below|
|IF||See 2 publications below|
19999-1-AP targets TGF beta 2-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse, rat, bovine|
|Host / Isotype||Rabbit / IgG|
|Full Name||transforming growth factor, beta 2|
|Calculated molecular weight||48 kDa|
|Observed molecular weight||48 kDa|
|GenBank accession number||NM_003238|
|Gene ID (NCBI)||7042|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Tranforming growth factor beta-2 (TGFB2), also named G-TSF, BSC-1 cell growth inhibitor, Polyergin and Cetermin, belongs to the TGF-beta family. TGFB2 is a secreted protein and contains a 19aa signal peptides at its N-terminal. Heterodimers with TGFB1 and with TGFB2 have been found in bone. It was proved to have suppressive effects on interleukin-2 dependent T-cell growth. This antibody is TGFB2 specific not detecting other TGFBs.
|Product Specific Protocols|
|WB protocol for TGF beta 2-Specific antibody 19999-1-AP||Download protocol|
|IHC protocol for TGF beta 2-Specific antibody 19999-1-AP||Download protocol|
|IF protocol for TGF beta 2-Specific antibody 19999-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Cell Death Differ
USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription.
Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer.
SIX1 promotes tumor lymphangiogenesis by coordinating TGFβ signals that increase expression of VEGF-C.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
J Exp Clin Cancer Res
LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer.
SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Kazu (Verified Customer) (12-14-2022)
A clear, single band at the expected molecular weight was observed by western blotting.