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TGF beta 2-Specific Polyclonal antibody
TGF beta 2-Specific Polyclonal Antibody for IF, IHC, WB, ELISA
Cat no : 19999-1-AP
Validation Data Gallery
|Positive WB detected in||HeLa cells, K-562 cells, mouse lung tissue, MCF-7 cells|
|Positive IHC detected in||human breast cancer tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Positive IF detected in||HeLa cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Immunofluorescence (IF)||IF : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
19999-1-AP targets TGF beta 2-Specific in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
|Tested Reactivity||human, mouse|
|Cited Reactivity||human, mouse, rat, bovine|
|Host / Isotype||Rabbit / IgG|
|Full Name||transforming growth factor, beta 2|
|Calculated molecular weight||48 kDa|
|Observed molecular weight||48 kDa|
|GenBank accession number||NM_003238|
|Gene ID (NCBI)||7042|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Tranforming growth factor beta-2 (TGFB2), also named G-TSF, BSC-1 cell growth inhibitor, Polyergin and Cetermin, belongs to the TGF-beta family. TGFB2 is a secreted protein and contains a 19aa signal peptides at its N-terminal. Heterodimers with TGFB1 and with TGFB2 have been found in bone. It was proved to have suppressive effects on interleukin-2 dependent T-cell growth. This antibody is TGFB2 specific not detecting other TGFBs.
|Product Specific Protocols|
|WB protocol for TGF beta 2-Specific antibody 19999-1-AP||Download protocol|
|IHC protocol for TGF beta 2-Specific antibody 19999-1-AP||Download protocol|
|IF protocol for TGF beta 2-Specific antibody 19999-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Gold Nanoparticles Induce Tumor Vessel Normalization and Impair Metastasis by Inhibiting Endothelial Smad2/3 Signaling.
Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway.
Cell Death Differ
USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription.
Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer.
SIX1 promotes tumor lymphangiogenesis by coordinating TGFβ signals that increase expression of VEGF-C.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Kazu (Verified Customer) (12-14-2022)
A clear, single band at the expected molecular weight was observed by western blotting.