|Positive WB detected in||A549 cells, A431 cells|
|Positive FC detected in||A549 cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
20000-1-AP targets TGFBR3-Specific in WB, IF, FC applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||transforming growth factor, beta receptor III|
|Calculated molecular weight||93 kDa|
|Observed molecular weight||110-150 kDa|
|GenBank accession number||NM_003243|
|Gene ID (NCBI)||7049|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
TGFBR3, also named as TGFR-3, BGCAN and betaglycan, binds to TGF-beta. TGFBR3 could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. This antibody is specific to TGFBR3.
Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway.
Vitamin D3 alleviates pulmonary fibrosis by regulating the MAPK pathway via targeting PSAT1 expression in vivo and in vitro.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Manfred (Verified Customer) (05-09-2022)
I highly recommend this anitbody. Protein of interest was detected at 94kDa.