|Positive WB detected in||A549 cells, A431 cells|
|Positive FC detected in||A549 cells|
|Western Blot (WB)||WB : 1:500-1:2000|
|Sample-dependent, check data in validation data gallery|
20000-1-AP targets TGFBR3-Specific in WB, IF, FC applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||transforming growth factor, beta receptor III|
|Calculated molecular weight||93 kDa|
|Observed molecular weight||110-150 kDa|
|GenBank accession number||NM_003243|
|Gene ID (NCBI)||7049|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.|
TGFBR3, also named as TGFR-3, BGCAN and betaglycan, binds to TGF-beta. TGFBR3 could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. This antibody is specific to TGFBR3.
Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway.
Vitamin D3 alleviates pulmonary fibrosis by regulating the MAPK pathway via targeting PSAT1 expression in vivo and in vitro.