TLE3 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 22094-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 42 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HEK-293 cells, HEK-293

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human lung cancer tissue, human breast cancer tissue, human lung cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

Calculated molecular weight:
772aa,83 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TLE3

Synonyms
ESG, ESG3, FLJ39460, GRG3, HsT18976, KIAA1547, TLE3
Background

Transducin-like enhancer of split 3(TLE3) is a corepressor that binds to a variant of transciption factor, which mediated by CTNNB1 and TCF family members in Wnt signaling. It's suggested that effect of full-length TLE family members be regulated by association with dominant-negative AES.


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