Anti-Mouse TNFRSF9/CD137 Rabbit Recombinant Antibody, PBS Only

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  FC experiment of mouse splenocytes using 98182-1-RR (same clone as 98182-1-PBS)

  1x10^6 untreated or Con A treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TNFRSF9/CD137 Rabbit Recombinant Antibody (98182-1-RR, Clone: 241647E11) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with APC Anti-Mouse CD25 (PC61.5) (APC-65137, Clone: PC61.5). Cells were not fixed. This data was developed using the same antibody clone with 98182-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98182-1-RR (same clone as 98182-1-PBS)

  1x10^6 Con A treated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TNFRSF9/CD137 Rabbit Recombinant Antibody (98182-1-RR, Clone: 241647E11) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TNFRSF9/CD137 Rabbit Recombinant Antibody (98182-1-RR, Clone: 241647E11) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 98182-1-PBS in a different storage buffer formulation.

TNFRSF9/CD137 Uni-rAb^TM Recombinant Antibody for FC

Cat No. 98182-1-PBS

Clone No.241647E11

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

Ly63, Ila, CD137, 4-1BB ligand receptor, 4-1BB

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Product Information

98182-1-PBS targets TNFRSF9/CD137 in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: FusionProtein
• Full Name: tumor necrosis factor receptor superfamily, member 9
• Calculated Molecular Weight: 28 kDa
• GenBank Accession Number: NM_001077509.1
• Gene Symbol: Tnfrsf9
• Gene ID (NCBI): 21942
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purfication
• UNIPROT ID: P20334
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)