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  • KD/KO Validated

TRPC6 Polyclonal antibody

TRPC6 Polyclonal Antibody for FC, IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IP, IHC, IF, FC,ELISA

Conjugate

Unconjugated

Cat no : 18236-1-AP

Synonyms

FSGS2, Transient receptor protein 6, TRP 6, TRP6, TRPC6



Tested Applications

Positive WB detected inmouse brain, COLO 320 cells, mouse lung tissue
Positive IP detected inmouse lung tissue
Positive IHC detected inhuman placenta tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive FC detected inA549 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 18236-1-AP is TRPC6 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRPC6 fusion protein Ag12976
Full Name transient receptor potential cation channel, subfamily C, member 6
Calculated molecular weight 931 aa, 106 kDa
Observed molecular weight 100-110 kDa
GenBank accession numberBC093658
Gene symbol TRPC6
Gene ID (NCBI) 7225
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
WB protocol for TRPC6 antibody 18236-1-APDownload protocol
IHC protocol for TRPC6 antibody 18236-1-APDownload protocol
IP protocol for TRPC6 antibody 18236-1-APDownload protocol
FC protocol for TRPC6 antibody 18236-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
ratWB

Lab Invest

Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats.

Authors - Xi He
mouseWB

Br J Pharmacol

Catalpol Alleviates Adriamycin-Induced Nephropathy by Activating the SIRT1 Signalling Pathway In Vivo and In Vitro.

Authors - Jiangnan Zhang
humanIF

Proc Natl Acad Sci U S A

TRPC6 channel translocation into phagosomal membrane augments phagosomal function.

Authors - Vladimir Riazanski
  • KO Validated
mouseWB,IF

Biomaterials

Nongenetic optical modulation of neural stem cell proliferation and neuronal/glial differentiation.

Authors - Meitian Wang
humanFC

Cell

Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis.

Authors - Wei Rao