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  • KD/KO Validated

TRPC6 Polyclonal antibody

TRPC6 Polyclonal Antibody for WB, IHC, IF/ICC, FC (Intra), IP, ELISA

Host / Isotype

Rabbit / IgG


human, mouse and More (1)





Cat no : 18236-1-AP


TRPC 6, TRP-6, TRP6, TRP 6, Transient receptor protein 6

Tested Applications

Positive WB detected inmouse brain, COLO 320 cells, mouse lung tissue
Positive IP detected inmouse lung tissue
Positive IHC detected inhuman placenta tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF/ICC detected inA549 cells
Positive FC (Intra) detected inA549 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:200-1:800
Flow Cytometry (FC) (INTRA)FC (INTRA) : 0.40 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

18236-1-AP targets TRPC6 in WB, IHC, IF/ICC, FC (Intra), IP, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TRPC6 fusion protein Ag12976
Full Name transient receptor potential cation channel, subfamily C, member 6
Calculated Molecular Weight 931 aa, 106 kDa
Observed Molecular Weight 100-110 kDa
GenBank Accession NumberBC093658
Gene Symbol TRPC6
Gene ID (NCBI) 7225
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Transient receptor potential canonical (TRPC) channels mediate the influx of different types of cations through the cell membrane and are involved in many functions of the organism (PMID: 28508319). The TRPC subfamily consists of seven members, TRPC1, TRPC2, TRPC3, TRPC4, TRPC5, TRPC6, TRPC7 (PMID: 32872338). TRPC6 is a Ca(2+)-permeable non-selective cation channel expressed in most human tissues. TRPC6 has been considered as potential therapeutic targets for malignant glioma treatment (PMID: 35489424).


Product Specific Protocols
WB protocol for TRPC6 antibody 18236-1-APDownload protocol
IHC protocol for TRPC6 antibody 18236-1-APDownload protocol
IF protocol for TRPC6 antibody 18236-1-APDownload protocol
IP protocol for TRPC6 antibody 18236-1-APDownload protocol
FC protocol for TRPC6 antibody 18236-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




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